Suppr超能文献

[剖腹术在霍奇金病治疗中的应用]

[Laparotomy in the therapy of Hodgkin's disease].

作者信息

Bauters F, Jouet J P, Caulier M T, Wurtz A, Ribet M, Goudemand M

出版信息

Nouv Rev Fr Hematol Blood Cells. 1977;18(2):495-502.

PMID:917838
Abstract

We have performed laparotomy and splenectomy for seventy patients with Hodgkin's disease. Among 43 stages I or II before exploration, primary laparotomy revealed ignored abdominal localizations in 16 cases (37,2%). Involvement of the spleen occurred in 13 of these 16 patients, lonely (5 cases), associated with positive nodes (4 cases) or associated with positive nodes and liver involvement (4 cases). Among 4 stages III before exploration, no regression was found. Among 9 patients with presumed stages I or II above the diaphragm and previously treated by radiotherapy, delayed laparotomy revealed abdominal relapse in 6 cases. At last, among 14 patients with obvious stages II or IV and previously treated by combination chemotherapy, laparotomy, caused by persistent evolutive signs, showed residual localizations under the diaphragm in 8 cases. According to these results, we preconise immediate laparotomy in almost all presumed stages I or II above the diaphragm. About third of these subjects have their staging advanced to stage III or IV and, according to us must be treated by combination chemotherapy while the remaining cases justify of radiotherapy. In obvious stages III and IV delayed laparotomy may be useful in some circumstances, after chemotherapy.

摘要

我们对70例霍奇金病患者进行了剖腹术和脾切除术。在术前处于Ⅰ期或Ⅱ期的43例患者中,初次剖腹术发现16例(37.2%)存在被忽视的腹部病变。这16例患者中有13例脾脏受累,单独脾脏受累(5例),合并淋巴结阳性(4例)或合并淋巴结阳性及肝脏受累(4例)。在术前处于Ⅲ期的4例患者中,未发现病情缓解。在9例术前推测为膈上Ⅰ期或Ⅱ期且先前接受过放疗的患者中,延迟剖腹术发现6例出现腹部复发。最后,在14例明显处于Ⅱ期或Ⅳ期且先前接受过联合化疗的患者中,因持续进展的体征而行剖腹术,结果显示8例患者在膈下有残留病变。根据这些结果,我们建议对几乎所有术前推测为膈上Ⅰ期或Ⅱ期的患者立即进行剖腹术。这些患者中约三分之一的分期会进展到Ⅲ期或Ⅳ期,依我们的观点,这些患者必须接受联合化疗,而其余患者则适合放疗。在明显的Ⅲ期和Ⅳ期,延迟剖腹术在某些情况下,化疗后可能有用。

相似文献

7
Pediatric Hodgkin's disease.小儿霍奇金病
J Ky Med Assoc. 2004 Mar;102(3):104-6.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验