Hung F C, Huang C B, Huang S C, Hsieh C S, Chuang J H
Department of Pediatrics, Chang Gung Children's Hospital, Kaohsiung, Taiwan, R.O.C.
Changgeng Yi Xue Za Zhi. 1997 Mar;20(1):29-33.
Necrotizing enterocolitis (NEC) is the most significant acquired gastrointestinal (GI) emergency in the neonatal intensive care unit.
We sought to gain a clinical perspective on NEC by reviewing the records of NEC patients over a 9-year period. The case histories of 22 infants with NEC treated from September 1, 1986 to September 1, 1995 were reviewed.
Mean gestational age was 32 weeks and mean birth weight was 1774 grams. Eighteen percent were full term babies and 82% were premature. Average age at the onset of NEC was 11 days. The most common clinical manifestations were abdominal distension (100%), gastric retention (64%), unstable vital signs (59%) and Guaiac-positive vomitus or stool (36%). Sixteen cases (73%) were classified as stage III NEC, which has the highest mortality and/or morbidity.
Early identification and management are critical to improve the outcome of NEC.
坏死性小肠结肠炎（NEC）是新生儿重症监护病房中最严重的后天性胃肠道急症。
我们通过回顾9年间NEC患者的记录，以获取关于NEC的临床观点。回顾了1986年9月1日至1995年9月1日期间接受治疗的22例NEC婴儿的病历。
平均胎龄为32周，平均出生体重为1774克。18%为足月儿，82%为早产儿。NEC发病的平均年龄为11天。最常见的临床表现为腹胀（100%）、胃潴留（64%）、生命体征不稳定（59%）和愈创木脂试验阳性的呕吐物或粪便（36%）。16例（73%）被归类为III期NEC，其死亡率和/或发病率最高。
早期识别和管理对于改善NEC的预后至关重要。
