朗格汉斯细胞组织细胞增多症中的复发性纵隔气肿和气胸。

Recurrent pneumomediastinum and pneumothorax in Langerhans cell histiocytosis.

作者信息

Yule S M, Hamilton J R, Windebank K P

机构信息

Children's Cancer Unit, Sir James Spence Department of Child Health, Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom.

出版信息

Med Pediatr Oncol. 1997 Aug;29(2):139-42. doi: 10.1002/(sici)1096-911x(199708)29:2<139::aid-mpo13>3.0.co;2-a.

DOI:10.1002/(sici)1096-911x(199708)29:2<139::aid-mpo13>3.0.co;2-a

PMID:9180917

Abstract

Pneumothorax is an unusual complication of pulmonary Langerhans cell histiocytosis. We report three children who developed recurrent intrathoracic air leaks. In one case, bilateral pneumothoraces may have been precipated by intermittent positive pressure ventilation during general anaesthesia. Chemical pleurodesis was unsuccessful in preventing recurrence of pneumothoraces in two children. The use of extracorporeal membrane oxygenation as an alternative to intermittent positive pressure ventilation in children with respiratory failure from Langerhans cell histiocytosis is discussed.

摘要

气胸是肺朗格汉斯细胞组织细胞增多症的一种罕见并发症。我们报告了三名出现反复胸腔内气体泄漏的儿童。在一例中，双侧气胸可能是由全身麻醉期间的间歇正压通气诱发的。化学性胸膜固定术在预防两名儿童气胸复发方面未获成功。本文讨论了在患有朗格汉斯细胞组织细胞增多症导致呼吸衰竭的儿童中，使用体外膜肺氧合替代间歇正压通气的情况。