Patiño J F
Universidad Nacional de Colombia.
Acta Gastroenterol Latinoam. 1996;26(3):187-92.
Cholelithiasis is a disease of high prevalence in the adult population. Prevalence increases with age; the incidence of complications, such as choledocholithiasis, acute pancreatitis, and cancer of gallbladder, also increase with age. Cholecystectomy has been considered as the gold standard in the treatment of symptomatic or complicated cholelithiasis. Laparoscopic cholecystectomy has become the new gold standard. Our Department of Surgery has adopted a policy of advising laparoscopic cholecystectomy in all patients with symptomatic cholelithiasis, but also subpopulation of high risk asymptomatic patients. This subgroup is made up by patients with long life expectancy, radioopaque stones, small calculus with patent cystic duct, nonfunctioning or calcified gall bladder, and patients with concomitant diabetes, cirrhosis, chronic hemolytic anemia, those that are candidates for kidney or heart transplantation, and those with underling degenerative diseases that are more likely to develop severe complication of cholelithiasis. Csendes of Chile has reported very high incidence of gallbladder cancer in Chile and Bolivia. He considers that cholecystectomy is indicated in asymptomatic patients as a "prophylactic" measure. Our group agrees that this is a valid indication in areas or populations groups where gallbladder cancer is of high prevalence.
胆结石是成年人群中一种高发性疾病。患病率随年龄增长而增加;胆总管结石、急性胰腺炎和胆囊癌等并发症的发生率也随年龄增长而增加。胆囊切除术一直被视为有症状或复杂性胆结石治疗的金标准。腹腔镜胆囊切除术已成为新的金标准。我们外科采用的策略是,建议所有有症状胆结石患者以及高风险无症状患者亚群进行腹腔镜胆囊切除术。该亚群包括预期寿命长、不透X线结石、胆囊管通畅的小结石、无功能或钙化胆囊的患者,以及合并糖尿病、肝硬化、慢性溶血性贫血的患者,肾或心脏移植候选者,以及那些患有基础退行性疾病且更易发生胆结石严重并发症的患者。智利的森德斯报告称,智利和玻利维亚胆囊癌发病率非常高。他认为,对无症状患者进行胆囊切除术作为一种“预防性”措施是必要的。我们团队同意,在胆囊癌高发地区或人群中,这是一个合理的指征。