Onoue S, Matsubara I, Nishizaki O, Kumon Y, Sakaki S
Department of Neurological Surgery, Saiseikai Saijo Hospital.
No Shinkei Geka. 1997 Jun;25(6):543-7.
We report a case of cranial osteomyelitis after head injury with exaggeration and remission for 30 years. A 41-year-old man was referred to our hospital with redness, swelling and pain in the left frontal region. He had noted a hard mass in the same region after an injury at the age of 12 years, and local heat and redness again in the same region which had disappeared without definite treatment at the age of 20 years. Presently, skull roentogenogram showed an erosive lesion in the left frontal bone. Plain CT revealed bone defect, epidural mass lesion, calcification of the dura mater and thickness of the extracranial soft tissue in the left frontal region. T1-weighted MR images showed an isointense lesion and T2-weighted MR images showed a high intensity lesion in the inner table and a diploic layer in the left frontal bone. 99thTc MDP bone scinntigram showed abnormal uptake in the same region. Operation performed through a left frontotemporal craniotomy revealed a degeneration of temporal muscle and frontal bone, and granulation tissue and pus in the subcutaneous and epidural spaces. These were removed together with the calcified dura mater. The subdural space was intact. Dural plasty was performed using fascia lata, but the craniotomied bone was replaced. Histological examination revealed typical findings of osteomyelitis. Postoperative course was uneventful, and he was discharged without neurological deficit. Cranioplasty was performed 8 months after the first surgery. The mechanism by which osteomyelitis continued over a long course of time was suspected to be the formation of a focus of recurrent inflammation due to the head injury 30 years earlier.
我们报告一例头部受伤后颅骨骨髓炎,病程长达30年,有病情加重与缓解情况。一名41岁男性因左额部红肿、疼痛被转诊至我院。他12岁头部受伤后在同一部位发现一硬块,20岁时该部位再次出现局部发热和发红,未经明确治疗后症状消失。目前,颅骨X线片显示左额骨有侵蚀性病变。普通CT显示骨缺损、硬膜外肿块病变、硬脑膜钙化以及左额部颅外软组织增厚。T1加权磁共振成像显示等信号病变,T2加权磁共振成像显示左额骨内板和板障层有高信号病变。99锝亚甲基二膦酸盐骨闪烁显像显示同一部位摄取异常。经左额颞开颅手术发现颞肌和额骨退变,皮下和硬膜外间隙有肉芽组织和脓液。将这些连同钙化的硬脑膜一并清除。硬膜下间隙完整。使用阔筋膜进行硬膜修补,但未放回开颅的骨片。组织学检查显示为典型的骨髓炎表现。术后病程顺利,患者出院时无神经功能缺损。首次手术后8个月进行了颅骨成形术。骨髓炎长期持续的机制被怀疑是30年前头部受伤导致反复炎症病灶形成。