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Tripeptide methylketones: synthesis and antiplasmin activity.

作者信息

Midura-Nowaczek K, Bruzgo I, Roszkowska-Jakimiec W, Worowski K

机构信息

Instytut Chemii, Uniwersytet Warszawski Filia w Białymstoku, Białystok, Poland.

出版信息

Farmaco. 1997 Jan;52(1):35-7.

PMID:9181679
Abstract

A series of tripeptide methylketones with C-terminal lysine was obtained via Dakin-West method and tested for their antiplasmin activity with the use of antifibrinolytic and antiamidolytic tests. The tripeptide methylketones has been found to inhibit plasmin, however with much lower potency than respective aldehydes.

摘要

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