Midura-Nowaczek K, Bruzgo I, Roszkowska-Jakimiec W, Worowski K
Institute of Chemistry, Branch of Warsaw University, Białystok.
Acta Pol Pharm. 1990;47(1-2):39-42.
Seven peptides of the general formula A-Phe-Lys-X or A-Phe-NH-(CH2)5-NH2 where A = Glp or Ala, X = -OH, -NHC7H15 or -OC7H15 were obtained. The peptide H-Ala-Phe-Lys-NHC7H15 markedly inhibits the fibrinolytic activity of plasmin. The antifibrinolytic activity of the peptide Glp-Phe-Lys-OC7H15 is similar to EACA. The both peptides only slightly activate the caseinolytic activity of plasmin.
