Synthesis of amides with anti-inflammatory and analgesic activities.
作者信息
Pau A, Cerri R, Boatto G, Palomba M, Pintore G, Filippelli W, Falcone G, Palagiano F, Rossi F
机构信息
Istituto di Analitica Farmaceutica, Università di Sassari, Italy.
出版信息
Farmaco. 1997 Feb;52(2):93-8.
PMID:9181689
Abstract
A series of N-Aroyl-cyclohexyl- and cyclohexenylamides 3- or 4-methylsubstituted were synthesized and evaluated for their anti-inflammatory and analgesic potencies, and gastrointestinal irritation liability. One compound, N-benzoyl-4-methyl-cyclohexylamide 6a, possessed an anti-inflammatory activity comparable to that of indomethacin.
摘要
Zotero 插件