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[获得性免疫缺陷综合征合并肺癌患者的长期生存情况]

[Long-term survival in patient with acquired immunodeficiency syndrome and adenocarcinoma of the lung].

作者信息

Pereira J R, Ikari F K, Nikaedo S M

机构信息

Serviço de Pneumologia, Instituto do Câncer Arnaldo, Vieira de Carvalho, São Paulo.

出版信息

Rev Assoc Med Bras (1992). 1996 Oct-Dec;42(4):258-60.

PMID:9181743
Abstract

BACKGROUND

Lung cancer associated with acquired immunodeficiency syndrome (AIDS) is unusual. Literature review between 1984 and 1993 showed less than 100 published cases of this association. From those cases it appears that the neoplasia is more aggressive and survival after diagnosis is less than 12 months. A case is reported of an HIV positive man with adenocarcinoma of the lung that survived 28 months after diagnosis, the longest published survival in such case described in the medical literature.

CASE REPORT

A 57-year old Caucasian homosexual male and heavy smoker was diagnosed as having a bronchogenic carcinoma and underwent right upper lobectomy, chemotherapy, thoracic surgery for carcinoma recurrence and radiotherapy. He remained in good condition with reasonable life quality and died for reasons unrelated either to his tumor or the antineoplastic treatment.

CONCLUSIONS

Diagnostic delay and the immuno-deficiency are the reasons for the dismal prognosis of lung cancer in AIDS patients. Aggressive treatment of the neoplastic disease should be done in such cases, as reasonable prolonged survival is possible, as shown by our report.

摘要

背景

与获得性免疫缺陷综合征(艾滋病)相关的肺癌并不常见。1984年至1993年的文献综述显示,已发表的此类关联病例不到100例。从这些病例来看,肿瘤更具侵袭性,诊断后的生存期不到12个月。本文报告了一例HIV阳性的肺癌腺癌患者,诊断后存活了28个月,这是医学文献中报道的此类病例中最长的生存期。

病例报告

一名57岁的白人同性恋男性,重度吸烟者,被诊断为支气管肺癌,接受了右上叶切除术、化疗、因癌症复发进行的胸外科手术和放疗。他一直状况良好,生活质量尚可,最终因与肿瘤或抗肿瘤治疗无关的原因死亡。

结论

诊断延迟和免疫缺陷是艾滋病患者肺癌预后不佳的原因。在这种情况下,应积极治疗肿瘤疾病,如我们的报告所示,合理延长生存期是可能的。

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