Katsuragi Naoya, Shiraishi Y, Nakajima Y, Kurai M, Takahashi N, Tanaka S
Section of Chest Surgery, Fukujuji Hospital, Kiyose, Japan.
Kyobu Geka. 2004 Aug;57(9):847-50.
Non-small cell lung cancer with syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is rare. A case of squamous bronchogenic carcinoma with SIADH is reported. A 64-year-old man was admitted with 2 cm nodule of the left lung on chest radiography. Transbronchial lung biopsy revealed the squamous cell carcinoma. His past history included hypertension and hemiparesis due to brain infarction. Serum sodium level was low (122 mEq/l) and serum osmolarity was low (271 mOsm/kgH2O). However, urine sodium level was high (82 mEg/l) and urine osmolarity was high (461 mOsm/kgH2O). Renal and adrenal function was normal. He was diagnosed with cT1N0M0 squamous bronchogenic carcinoma accompanied by SIADH. He underwent left upper lobectomy with lymph node dissection. Five months after the operation, serum sodium level returned to normal. He remains well 20 months after the operation.
伴有抗利尿激素分泌不当综合征（SIADH）的非小细胞肺癌较为罕见。本文报告一例伴有SIADH的鳞状支气管癌病例。一名64岁男性因胸部X线检查发现左肺有2cm结节入院。经支气管肺活检显示为鳞状细胞癌。他既往有高血压病史，曾因脑梗死导致偏瘫。血清钠水平低（122 mEq/l），血清渗透压低（271 mOsm/kgH2O）。然而，尿钠水平高（82 mEg/l），尿渗透压高（461 mOsm/kgH2O）。肾和肾上腺功能正常。他被诊断为cT1N0M0鳞状支气管癌伴SIADH。他接受了左上肺叶切除及淋巴结清扫术。术后五个月，血清钠水平恢复正常。术后20个月他情况良好。
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