Kwaśniewska A, Tukendorf A, Semczuk M
Klinika Połoznictwa i Patologii Ciazy Akademii Medycznej w Lublinie.
Med Dosw Mikrobiol. 1996;48(3-4):183-8.
The effect of HPV infection on cervix dysplasia development and ascorbic acid level in 528 women was studied. HPV-DNA was estimated using Digene Hybride Capture System and ascorbic acid by color metric method with 2,4-dinitrophenylhydrazine at 520 nm. HPV infection can be connected with the risk of cervical pathology and cervical cancer. Besides, we observed lower level of ascorbic acid in groups of women with CIN, Ca in situ and HPV infected.
研究了528名女性中HPV感染对宫颈发育异常及抗坏血酸水平的影响。采用Digene杂交捕获系统检测HPV-DNA,用2,4-二硝基苯肼比色法在520nm波长下测定抗坏血酸。HPV感染可能与宫颈病变和宫颈癌风险相关。此外,我们观察到患有CIN、原位癌和HPV感染的女性组中抗坏血酸水平较低。