膳食摄入草酸对雄性和雌性长 Evans 大鼠生长和繁殖的影响。

Effect of dietary ingestion of oxalic acid on growth and reproduction in male and female Long-Evans rats.

作者信息

Goldman M, Doering G J, Nelson R G

出版信息

Res Commun Chem Pathol Pharmacol. 1977 Oct;18(2):369-72.

Abstract

Male and female Long-Evans rats placed on a diet of Purina laboratory chow supplemented with 2.5 and 5.0% oxalic acid for a period of 70 days revealed decreased body weights and restricted growth rates. Ingestion of 5.0% oxalic acid depressed absolute organ weights of several visceral and endocrine tissues but enhanced the organ/body weight ratios of both male and female rats. Vaginal smears indicated disrupted estrous cycles.

摘要

给雄性和雌性长 Evans 大鼠喂食添加了 2.5%和 5.0%草酸的普瑞纳实验室饲料，为期 70 天，结果显示大鼠体重下降，生长速度受限。摄入 5.0%草酸会降低多个内脏和内分泌组织的绝对器官重量，但会提高雄性和雌性大鼠的器官/体重比。阴道涂片显示发情周期紊乱。