Carmeliet P, Collen D
Center for Transgene Technology and Gene Therapy, Flanders Interuniversity Institute of Biotechnology, Leuven, Belgium.
Curr Opin Lipidol. 1997 Apr;8(2):118-25. doi: 10.1097/00041433-199704000-00010.
The plasminogen and coagulation systems have been extensively characterized at the biochemical level. Recent gene targeting and gene transfer studies have provided novel insights into their role in the formation of blood vessels and in the pathogenesis of blood vessel disorders including thrombosis, restenosis and atherosclerosis.
纤溶酶原和凝血系统在生化水平上已得到广泛研究。最近的基因靶向和基因转移研究为它们在血管形成以及包括血栓形成、再狭窄和动脉粥样硬化在内的血管疾病发病机制中的作用提供了新的见解。
