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饲喂不同水平鱼油日粮的蓝狐(北极狐)和水貂(鼬属)肝脏脂肪酸组成及过氧化物酶体脂肪酸氧化酶活性

Liver fatty acid composition and peroxisomal fatty acid oxidase activity in blue foxes (Alopex lagopus) and mink (Mustela vison) fed diets containing different levels of fish oil.

作者信息

Ahlstrøm O, Skrede A

机构信息

Department of Animal Science, Agricultural University of Norway, As, Norway.

出版信息

Comp Biochem Physiol A Physiol. 1997 May;117(1):135-40. doi: 10.1016/s0300-9629(96)00287-3.

DOI:10.1016/s0300-9629(96)00287-3
PMID:9185341
Abstract

At the time of pelting (Nov.), blue foxes had a lower liver lipid content (4-5%) than mink (7-10%), whereas the phospholipid (PL) content was 0.5-1% in both species. Dietary fat content had little influence on total liver fat content but affected the liver fatty acid composition. Levels of n3 fatty acids were higher in the PL fraction than in the remaining fraction of liver lipids in both species. Because PL accounted for a larger part of the total liver lipids in blue foxes than in mink, the proportion of the total liver lipids accounted for by n3 fatty acids was highest in blue foxes. On the other hand, the mink and foxes had about the same quantity of n3 per gram liver owing to higher fat content of mink liver. Analyses of liver lipid fatty acid composition did not reveal any differences between the species in their ability to metabolize n3 fatty acids originating from fish oil. Peroxisomal beta-oxidation activity in the liver was significantly higher in blue foxes than in mink. For both species the total activity rose as the level of dietary fish oil increased.

摘要

在脱毛期(11月),蓝狐肝脏脂质含量(4 - 5%)低于水貂(7 - 10%),而两种动物的磷脂(PL)含量均为0.5 - 1%。日粮脂肪含量对肝脏总脂肪含量影响较小,但会影响肝脏脂肪酸组成。两种动物中,PL部分的n3脂肪酸水平均高于肝脏脂质的其余部分。由于蓝狐肝脏中PL占总肝脏脂质的比例高于水貂,所以蓝狐肝脏脂质中n3脂肪酸占总肝脏脂质的比例最高。另一方面,由于水貂肝脏脂肪含量较高,每克肝脏中n3的含量在水貂和蓝狐中大致相同。肝脏脂质脂肪酸组成分析未显示出两种动物在代谢源自鱼油的n3脂肪酸能力上存在差异。蓝狐肝脏中的过氧化物酶体β - 氧化活性显著高于水貂。对于两种动物,随着日粮鱼油水平的增加,总活性均上升。

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