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耐甲氧西林金黄色葡萄球菌综述,特别涉及外科手术患者的处理

Review of methicillin resistant Staphylococcus aureus with special reference to handling of surgical patients.

作者信息

Gakuu L N

机构信息

Department of Orthopaedic Surgery, University of Nairobi, Kenya.

出版信息

East Afr Med J. 1997 Mar;74(3):198-202.

PMID:9185423
Abstract

If used rationally, antibiotics can cure most bacterial infections. However, there is an increasing tendency globally for bacteria to become resistant to antibiotics. In Kenya, the occurrence of methicillin resistant Staphylococcus aureus(MRSA) is becoming increasingly prevalent. Penicillin, despite its narrow antibacterial spectrum, is still widely used in developing countries in prophylaxis as well as in curative settings. In surgical patients, antibiotic resistance is seen in: patients who are immunosuppressed, patients who have extensive burns and compound fractures, patients requiring prolonged hospital stay and those with malnutrition and low serum albumen levels. Various forms of theatre inadequacies may also result into antibiotic resistance. There are many methods of controlling the spread of MRSA and they should be put into place in surgical units with the assistance of infection control units. This paper is a review of MRSA as regards its history, prevalence, modes of transmission, surveillance, control measures, treatment and implications for both health care workers and patients.

摘要

如果合理使用,抗生素可以治愈大多数细菌感染。然而,全球范围内细菌对抗生素产生耐药性的趋势正在增加。在肯尼亚,耐甲氧西林金黄色葡萄球菌(MRSA)的出现越来越普遍。青霉素尽管抗菌谱较窄,但仍在发展中国家广泛用于预防和治疗。在外科手术患者中,抗生素耐药性见于:免疫抑制患者、大面积烧伤和复合骨折患者、需要长期住院的患者以及营养不良和血清白蛋白水平低的患者。手术室的各种不足也可能导致抗生素耐药性。有许多控制MRSA传播的方法,应在感染控制部门的协助下在外科病房实施。本文是关于MRSA的历史、流行情况、传播方式、监测、控制措施、治疗以及对医护人员和患者的影响的综述。

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