多次输血患者血小板5-羟色胺释放试验的补体依赖性
Complement-dependence of platelet serotonin release test in polytransfused patients.
作者信息
Gandolfo G M, Afeltra A, Mannella E, Costantini G
出版信息
Scand J Haematol. 1977 Oct;19(4):355-9. doi: 10.1111/j.1600-0609.1977.tb01486.x.
The research of platelet isoantibodies in patients with Cooley's anaemia was performed by simultaneous determination of the platelet-complement fixation test, platelet factor 3 availability assay and 14C-serotonin release test. In 93% of the examined patients we obtained positive results with the 5HT-release test, which appeared to be a complement-dependent reaction in most of the sera-containing isoantibodies, different from sera of patients affected by autoimmune thrombocytopenia.
通过同时测定血小板补体结合试验、血小板第3因子有效性测定和14C-5-羟色胺释放试验，对库利贫血患者的血小板同种抗体进行了研究。在93%的受检患者中，5-羟色胺释放试验获得了阳性结果，在大多数含有同种抗体的血清中，该试验似乎是一种补体依赖反应，这与自身免疫性血小板减少症患者的血清不同。
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