Jackson J A, Chart I S, Sanderson J H, Garner R
Scand J Haematol. 1977 Oct;19(4):360-6. doi: 10.1111/j.1600-0609.1977.tb01487.x.
The feeding of pirimicarb (2-dimethylamino-5,6-dimethylpyrimidin-4-yl dimethylcarbamate) to normal beagle dogs resulted in anaemia in a small number of animals. Dosing studies confirmed pirimicarb as the causative agent and the anaemia was characterised as haemolytic. Serological tests revealed the presence of an IgG antibody active only in the presence of pirimicarb. The level of antibody detected was related to the dose of pririmicarb given.
给正常的比格犬喂食抗蚜威(2-二甲基氨基-5,6-二甲基嘧啶-4-基二甲基氨基甲酸酯)导致少数动物出现贫血。剂量研究证实抗蚜威是致病因素,且贫血表现为溶血性。血清学检测显示存在一种仅在抗蚜威存在时才具有活性的IgG抗体。检测到的抗体水平与所给予的抗蚜威剂量有关。