Flubacher P, Meier V, Obrecht J P, Hartmann D
Schweiz Med Wochenschr. 1977 Oct 8;107(40):1412-7.
A 69-year-old patient treated with anticancer polychemotherapy for metastatic breast carcinoma died of respiratory distress and cardiac failure 3 months after commencement of therapy. At autopsy only a few pleural micrometastases were found. Microscopic study revealed early lung lesions due to cytotoxic drug treatment. While the earlier literature described different lesions associated with different antineoplastic drugs (busulfan, bleomycin), today there is more emphasis on the common pathological features. Therefore, instead of the expressions "busulfan lung" or "bleomycin lung", we suggest the use of the term "Zytostatika-Pneumopathie" (cytostatic drug induced lung disease).
一名69岁接受转移性乳腺癌多药联合抗癌化疗的患者在治疗开始3个月后死于呼吸窘迫和心力衰竭。尸检仅发现少数胸膜微转移灶。显微镜检查显示为细胞毒性药物治疗引起的早期肺部病变。虽然早期文献描述了与不同抗肿瘤药物（白消安、博来霉素）相关的不同病变，但如今更强调其共同的病理特征。因此，我们建议不再使用“白消安肺”或“博来霉素肺”等表述，而是使用“细胞毒性药物所致肺病”这一术语。
