Dudek B, Merecz D
Department of Work Psychology, Nofer Institute of Occupational Medicine, Lódź, Poland.
Int J Occup Med Environ Health. 1997;10(1):37-46.
The major objective of the study was to determine whether environmental exposure to lead exerts a negative impact upon psychological functions in children. The examined group consisted fo school age children (6-15 years old, x = 9.5, SD = 1.4) living close to copper works. Out of 4548 children with measured blood lead concentrations, two groups were selected one with the highest exposure levels (12.0-27.2 micrograms/dl) and the other drawn from the remaining children, with low blood lead levels. The mean exposure level for the whole examined group equalled 10.18 mu/dl PbB (SD-4.73 micrograms/dl). To assess effects of the exposure, the following variables were measured in the examined children: intelligence, hand-eye coordination, perception, memory, reaction time and accuracy, and behaviour disorders. The moderator variables of sociodemographic character, i.e. parents' education, income, etc., were also controlled. A significant impact of lead upon psychological functions and behaviour was revealed for two variables only: intelligence and attention concentration. An increase in the exposure level by 10 micrograms/dl PbB was associated with deterioration of general IQ by 5.3 points and growth of the number of mistakes in the Simple Reaction Time test by 3.3. It was also revealed that the short-term memory deteriorates with growing level of exposure, the strength of this relationship was close to the level of statistical significance (p < 0.07).
该研究的主要目的是确定儿童环境铅暴露是否会对其心理功能产生负面影响。被检查的群体包括居住在铜厂附近的学龄儿童(6至15岁,x = 9.5,标准差 = 1.4)。在4548名测量了血铅浓度的儿童中,选取了两组,一组是血铅暴露水平最高的(12.0至27.2微克/分升),另一组是从其余血铅水平低的儿童中抽取的。整个被检查群体的平均暴露水平为10.18微克/分升血铅(标准差 - 4.73微克/分升)。为了评估暴露的影响,对被检查儿童测量了以下变量:智力、手眼协调能力、感知能力、记忆力、反应时间和准确性以及行为障碍。社会人口学特征的调节变量,即父母的教育程度、收入等,也得到了控制。仅在两个变量上发现铅对心理功能和行为有显著影响:智力和注意力集中程度。血铅暴露水平每增加10微克/分升,一般智商就会下降5.3分,简单反应时间测试中的错误数量就会增加3.3。还发现短期记忆随着暴露水平的升高而下降,这种关系的强度接近统计学显著性水平(p < 0.07)。