艾滋病痴呆症与载脂蛋白E
HIV dementia and apolipoprotein E.
作者信息
Dunlop O, Goplen A K, Liestøl K, Myrvang B, Rootwelt H, Christophersen B, Kvittingen E A, Maehlen J
机构信息
Department of Infectious Diseases, Ullevål University Hospital, Oslo, Norway.
出版信息
Acta Neurol Scand. 1997 May;95(5):315-8. doi: 10.1111/j.1600-0404.1997.tb00217.x.
The effect of apolipoprotein E genotypes on the occurrence of HIV dementia and HIV encephalitis was studied in a sample of 132 AIDS patients in whom clinical data on dementia was available and full autopsy had been performed. There was no statistically significant correlation between risk of HIV dementia or HIV encephalitis in relation to apolipoprotein E genotypes, even after correction for length of survival with AIDS and antiretroviral treatment.
在132例艾滋病患者样本中，研究了载脂蛋白E基因型对HIV痴呆和HIV脑炎发生情况的影响，这些患者有痴呆的临床数据且已进行了完整尸检。即使校正了艾滋病存活时间和抗逆转录病毒治疗因素，载脂蛋白E基因型与HIV痴呆或HIV脑炎风险之间也没有统计学上的显著相关性。
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