Kissinger J C, Hahn J H, Raff R A
Department of Biology, Indiana University, Bloomington 47405, USA.
Mol Biol Evol. 1997 Jun;14(6):654-65. doi: 10.1093/oxfordjournals.molbev.a025805.
Camarodont sea urchins possess a rapidly evolving actin gene family whose members are expressed in distinct cell lineages in a developmentally regulated fashion. Evolutionary changes in the actin gene family of echinoids include alterations in number of family members, site of expression, and gene linkage, and a dichotomy between rapidly and slowly evolving isoform-specific 3' untranslated regions. We present sequence comparisons and an analysis of the actin gene family in two congeneric sea urchins that develop in radically different modes, Heliocidaris erythrogramma and H. tuberculata. The sequences of several actin genes from the related species Lytechinus variegatus are also presented. We compare the features of the Heliocidaris and Lytechinus actin genes to those of the the actin gene families of other closely related sea urchins and discuss the nature of the evolutionary changes among sea urchin actins and their relationship to developmental mode.
拱齿目海胆拥有一个快速进化的肌动蛋白基因家族，其成员以发育调控的方式在不同的细胞谱系中表达。海胆类肌动蛋白基因家族的进化变化包括家族成员数量、表达位点和基因连锁的改变，以及快速进化和缓慢进化的同工型特异性3'非翻译区之间的二分法。我们展示了两种以截然不同的方式发育的同属海胆——红斑海胆（Heliocidaris erythrogramma）和瘤海胆（H. tuberculata）的肌动蛋白基因家族的序列比较和分析。还展示了来自相关物种多疣丽海胆（Lytechinus variegatus）的几个肌动蛋白基因的序列。我们将红斑海胆和丽海胆的肌动蛋白基因特征与其他亲缘关系密切的海胆的肌动蛋白基因家族特征进行比较，并讨论海胆肌动蛋白之间进化变化的性质及其与发育模式的关系。
