Yeung K K, Weissman B A
University of California, Los Angeles 90095-7002, USA.
J Am Optom Assoc. 1997 Jun;68(6):367-72.
Marfan syndrome, a genetic connective tissue disorder, manifests many problems: high myopia, astigmatism, crystalline lens subluxation, and cataracts. No published studies have described the contact lens corrections that can be used with Marfan syndrome patients. This report describes the variety of contact lens modalities used for a subpopulation of patients with Marfan syndrome.
The clinical records of eight patients with Marfan syndrome (16 eyes) from two hospital-based contact lens practices were retrospectively reviewed. Seven different contact lens modalities were used for this subpopulation.
Mean unaided visual acuities were 20/296, while mean best-corrected optimal spectacle refraction visual acuities were 20/33. Contact lenses improved the mean visual acuity to 20/27. Patients wore the contact lenses for an average of 12 hours per day. Complications of contact lens wear occurred in approximately 70% of eyes and included neovascularization, giant papillary conjunctivitis, 3 and 9 o'clock staining, and central superficial punctate staining. Additionally, ocular non-contact lens-related complications occurred in 50% of patients.
A variety of contact lens designs may be used during the care of patients with Marfan syndrome. However, patients may experience an increased rate of complications associated with contact lens wear or unrelated to lens wear, and thus they deserve more intensive follow-up care than non-Marfan syndrome patients.
马凡综合征是一种遗传性结缔组织疾病，表现出许多问题：高度近视、散光、晶状体半脱位和白内障。尚无已发表的研究描述可用于马凡综合征患者的隐形眼镜矫正方法。本报告描述了用于马凡综合征患者亚群的多种隐形眼镜类型。
回顾性分析了来自两家医院隐形眼镜诊所的8例马凡综合征患者（16只眼）的临床记录。该亚群使用了七种不同的隐形眼镜类型。
平均裸眼视力为20/296，而平均最佳矫正验光视力为20/33。隐形眼镜将平均视力提高到20/27。患者每天平均佩戴隐形眼镜12小时。约70%的眼睛出现了隐形眼镜佩戴并发症，包括新生血管形成、巨大乳头性结膜炎、3点和9点染色以及中央浅层点状染色。此外，50%的患者出现了与隐形眼镜无关的眼部并发症。
在马凡综合征患者的护理过程中可使用多种隐形眼镜设计。然而，患者可能会出现与隐形眼镜佩戴相关或无关的并发症发生率增加的情况，因此他们比非马凡综合征患者需要更密切的随访护理。
