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[纤维支气管镜检查和支气管肺泡灌洗(BAL)对肺量计测量结果的影响]

[The effect of fiberoptic bronchoscopy and bronchoalveolar lavage (BAL) on results of spirometric measurements].

作者信息

Michnar M, Kieszko R, Lupina T, Milanowski J

机构信息

Katedra i Klinika Chorób Płuc i Gruźlicy, Akademii Medycznej w Lublinie.

出版信息

Pneumonol Alergol Pol. 1996;64 Suppl 1:97-103.

PMID:9190246
Abstract

The effect of fiberoptic bronchoscopy and bronchoalveolar lavage on the functioning of the respiratory system was studied in 72 patients (42 males and 30 females). The bronchoscopy was performed in the sitting position. Supplemental oxygen was not given to all the evaluated patients. The group included 24 patients with lung cancer, 9 with sarcoidosis, 12 with tuberculosis, 1 with farmer's lung and 10 with other lung diseases (pneumonia, COPD). A control group consisted of 16 patients who were undergoing routine diagnostic endoscopy but who were seen to be without lung disease. Group BF (39 individuals) received only a bronchoscopic examination, group BF+BAL (33 persons) received a bronchoscopy followed by BAL using 140 ml. of normal saline solution as a lavage fluid. After the bronchoscopic examination there were significant differences in all spirometric measurements, except MEF25. The bronchoscopy and bronchoalveolar lavage caused a transient fall in FEV1, VC, MEF50, MEF75 (7.7-9.4%) which was similar in both groups. These measurements returned to normal after 24 hours. The testing of pulmonary functioning before the bronchoscopy was seen to be clinically important for safety of the patient undergoing this procedure.

摘要

在72例患者(42例男性和30例女性)中研究了纤维支气管镜检查和支气管肺泡灌洗对呼吸系统功能的影响。支气管镜检查在坐位进行。并非所有接受评估的患者都给予了补充氧气。该组包括24例肺癌患者、9例结节病患者、12例结核病患者、1例农民肺患者和10例其他肺部疾病(肺炎、慢性阻塞性肺疾病)患者。一个对照组由16例正在接受常规诊断性内镜检查但被认为无肺部疾病的患者组成。BF组(39人)仅接受支气管镜检查,BF + BAL组(33人)接受支气管镜检查,随后使用140毫升生理盐水作为灌洗液体进行BAL。支气管镜检查后,除MEF25外,所有肺量计测量值均有显著差异。支气管镜检查和支气管肺泡灌洗导致FEV1、VC、MEF50、MEF75短暂下降(7.7 - 9.4%),两组相似。这些测量值在24小时后恢复正常。支气管镜检查前的肺功能测试对于接受该手术的患者的安全性具有临床重要性。

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