Osadchiĭ L I, Balueva T V, Sergeev I V
Aviakosm Ekolog Med. 1997;31(2):20-4.
Contribution of the original angiotensin-2 controlled arterial tone to the shifts in systolic and diastolic arterial pressure (AP) was assessed in unconscious rats during tail-suspension. With this technique, values of original mean AP were elevated from 80-110 to 111-140 mm Hg. In the head-down position, rise in the tone was concurrent to a twofold increase in the number of "uncompensated" responses and a similar decrease in the number of test-resistant responses. The original arterial tone high, maximum decline of diastolic pressure was significantly less pronounced. Recovery of both systolic and diastolic arterial pressures was more dynamic against the background of high original tone. Magnitude of the diastolic AP variation dominated over that of systolic AP. These results are being analyzed in comparison with the data about orthostatic compensatory reactions.
在尾部悬吊的无意识大鼠中，评估了原始血管紧张素-2控制的动脉张力对收缩压和舒张压（AP）变化的影响。采用该技术，原始平均动脉压值从80 - 110 mmHg升高至111 - 140 mmHg。在头低位时，张力升高与“未代偿”反应数量增加两倍以及抗试验反应数量类似减少同时出现。原始动脉张力高时，舒张压的最大下降明显不那么显著。在高原始张力背景下，收缩压和舒张压的恢复更具动态性。舒张压AP变化幅度大于收缩压AP变化幅度。将这些结果与关于直立性代偿反应的数据进行了比较分析。
