Grzybowski A, Breborowicz A
Katedry i Zakładu Patofizjologii, Akademii Medycznej w Poznaniu.
Przegl Lek. 1997;54(1):52-61.
Peritoneal dialysis is an established method of treatment of chronic renal failure. In that paper morphological and functional changes of peritoneum due to the process of long-term dialysis are presented. Morphological changes are observed in mesothelial cells, intercellular junctions, interstitial tissue and blood vessels. Moreover morphological changes in typical complications of chronic peritoneal dialysis, e. g. peritonitis, eosinophilic peritonitis, and sclerosing encapsulating peritonitis are described. Mechanisms of functional disorders during chronic peritoneal dialysis, involving the decreased permeability of the peritoneum, the increased permeability of the peritoneum and the enhanced lymphatic drainage are discussed. The article is the second of two parts presenting physiology and pathology of peritoneum as dialysis membrane.
腹膜透析是治疗慢性肾衰竭的一种既定方法。该论文阐述了长期透析过程中腹膜的形态和功能变化。观察到间皮细胞、细胞间连接、间质组织和血管的形态变化。此外，还描述了慢性腹膜透析典型并发症（如腹膜炎、嗜酸性粒细胞性腹膜炎和硬化性包裹性腹膜炎）的形态变化。讨论了慢性腹膜透析期间功能障碍的机制，包括腹膜通透性降低、腹膜通透性增加和淋巴引流增强。本文是关于腹膜作为透析膜的生理学和病理学的两篇系列文章中的第二篇。
