苹果酸脱氢酶（MDHs）的结构研究：短波单胞菌属中的MDHs是变形菌门中首次报道的MDHs，其一级结构类似于乳酸脱氢酶。
Structural studies of malate dehydrogenases (MDHs): MDHs in Brevundimonas species are the first reported MDHs in Proteobacteria which resemble lactate dehydrogenases in primary structure.
作者信息
Charnock C
机构信息
Department of Microbiology, Institute of Pharmacy, University of Oslo, Blindern, Norway.
出版信息
J Bacteriol. 1997 Jun;179(12):4066-70. doi: 10.1128/jb.179.12.4066-4070.1997.
Abstract
The N-terminal sequences of malate dehydrogenases from 10 bacterial strains, representing seven genera of Proteobacteria, were determined. Of these, the enzyme sequences of species classified in the genus Brevundimonas clearly resembled those malate dehydrogenases with greatest similarity to lactate dehydrogenases. Additional evidence from subunit molecular weights, peptide mapping, and enzyme mobilities suggested that malate dehydrogenases from species of the genus Brevundimonas were structurally distinct from others in the study.
摘要
测定了代表变形菌门七个属的10个细菌菌株苹果酸脱氢酶的N端序列。其中，短波单胞菌属分类物种的酶序列明显类似于与乳酸脱氢酶具有最大相似性的那些苹果酸脱氢酶。来自亚基分子量、肽图谱和酶迁移率的其他证据表明，短波单胞菌属物种的苹果酸脱氢酶在结构上与该研究中的其他酶不同。
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