一个枯草芽孢杆菌苹果酸脱氢酶基因。
A Bacillus subtilis malate dehydrogenase gene.
作者信息
Jin S, De Jesús-Berríos M, Sonenshein A L
机构信息
Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts 02111, USA.
出版信息
J Bacteriol. 1996 Jan;178(2):560-3. doi: 10.1128/jb.178.2.560-563.1996.
Abstract
A Bacillus subtilis gene for malate dehydrogenase (citH) was found downstream of genes for citrate synthase and isocitrate dehydrogenase. Disruption of citH caused partial auxotrophy for aspartate and a requirement for aspartate during sporulation. In the absence of aspartate, citH mutant cells were blocked at a late stage of spore formation.
摘要
在柠檬酸合酶和异柠檬酸脱氢酶基因的下游发现了一个枯草芽孢杆菌苹果酸脱氢酶基因（citH）。citH的破坏导致对天冬氨酸的部分营养缺陷以及在孢子形成过程中对天冬氨酸的需求。在没有天冬氨酸的情况下，citH突变细胞在孢子形成的后期被阻断。
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