Smirnov E A
Vopr Onkol. 1977;23(6):20-6.
The author describes two observations on cancerous alveolitis and bronchiolitis developed in the foci of chronic (interstitial) pneumonia under squamous metaplasia and anaplasia of epithelial cells of alveoli and bronchioli. Two cases were diagnosed by roentgenologists, one case was found pathoanatomically; in the first two cases the patients died due to grave hypoxia and cardiopulmonary insufficiency, in the third case-due to encephalomalacia in ischemic brain disease. Cancerous alveolitis and bronchiolitis made 2.4% to all lung cancer, the disease shows an acute course, the duration of the lesion-4-6-months.
作者描述了在慢性(间质性)肺炎病灶中,肺泡和细支气管上皮细胞发生鳞状化生和间变时出现的癌性肺泡炎和细支气管炎的两项观察结果。两例由放射科医生诊断,一例经病理解剖发现;在前两例中,患者因严重缺氧和心肺功能不全死亡,第三例因缺血性脑病导致脑软化死亡。癌性肺泡炎和细支气管炎占所有肺癌的2.4%,该病呈急性病程,病变持续时间为4至6个月。