Smirnov E A
Vopr Onkol. 1978;24(2):93-5.
The studies performed have indicated that nearly in 50% of cases lung cancer is associated with different chronic lesions of the lung: chronic purulent bronchitis, tuberculosis, chronic pneumonia, pulmonary emphysema and diffuse pneumosclerosis, and these provide favourable conditions for epithelial metaplasia of the bronchi, bronchioli and alveoli with subsequent cell atypism and development of lung cancer.
已开展的研究表明，近50%的肺癌病例与肺部的不同慢性病变有关：慢性化脓性支气管炎、肺结核、慢性肺炎、肺气肿和弥漫性肺硬化，这些病变为支气管、细支气管和肺泡的上皮化生提供了有利条件，随后出现细胞异型性并发展为肺癌。
