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粉末对感染风险的影响及相关机制。

Effects of powder on infection risks and associated mechanisms.

作者信息

Renz H, Gemsa D

机构信息

Laboratory Medicine and Immunopathology, Humboldt University of Berlin, Germany.

出版信息

Eur J Surg Suppl. 1997(579):35-8.

PMID:9195182
Abstract

This paper examines the release of Tumour necrosis factor alpha, (TNFa) interleukin 1, eicosanoids, and hydrogen peroxide from macrophages exposed to glove starch particles. Studies are described which show that T-cell responses are potently activated by glove powder products leading to the release and formation of high amounts of pro-inflammatory mediators, ultimately resulting in adverse clinical consequences such as starch peritonitis or adhesions.

摘要

本文研究了暴露于手套淀粉颗粒的巨噬细胞释放肿瘤坏死因子α(TNFα)、白细胞介素1、类花生酸和过氧化氢的情况。所描述的研究表明,手套粉末产品可有效激活T细胞反应,导致大量促炎介质的释放和形成,最终引发如淀粉性腹膜炎或粘连等不良临床后果。

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