Renz H, Gemsa D
Laboratory Medicine and Immunopathology, Humboldt University of Berlin, Germany.
Eur J Surg Suppl. 1997(579):35-8.
This paper examines the release of Tumour necrosis factor alpha, (TNFa) interleukin 1, eicosanoids, and hydrogen peroxide from macrophages exposed to glove starch particles. Studies are described which show that T-cell responses are potently activated by glove powder products leading to the release and formation of high amounts of pro-inflammatory mediators, ultimately resulting in adverse clinical consequences such as starch peritonitis or adhesions.
本文研究了暴露于手套淀粉颗粒的巨噬细胞释放肿瘤坏死因子α(TNFα)、白细胞介素1、类花生酸和过氧化氢的情况。所描述的研究表明,手套粉末产品可有效激活T细胞反应,导致大量促炎介质的释放和形成,最终引发如淀粉性腹膜炎或粘连等不良临床后果。