Dhakal M P, Kallay M C, Talley T E
Renal and Pulmonary Unit, Highland Hospital, Rochester, New York, USA.
Int J Artif Organs. 1997 Apr;20(4):204-7.
To investigate whether hypoxia extends into the post-hemodialysis period, nine clinically stable-end stage renal disease patients were dialyzed against bicarbonate and one against an acetate batch, all with bioincompatible dialyzers. None had clinical evidence of cardiopulmonary overload on the day of the study. Using an oximeter with internal memory, oxygen saturation was monitored continuously at the beginning, during, and for four hours after hemodialysis. Hypoxia was defined as oxygen saturation less than 85%. Three patients had no hypoxia during or after dialysis. Hypoxia occurred in five patients both during and after dialysis, and in two patients only in the post-dialysis period. Episodes of hypoxia were of longer duration and severity in post-dialysis period. We conclude that significant hypoxia can occur in the post-hemodialysis period.
为了研究低氧血症是否会延续到血液透析后阶段，对9例临床病情稳定的终末期肾病患者使用生物不相容透析器进行碳酸氢盐透析，1例患者使用醋酸盐批次透析。在研究当天，所有患者均无心肺负荷过重的临床证据。使用具有内部存储器的血氧饱和度测定仪，在血液透析开始时、透析期间以及透析后4小时连续监测血氧饱和度。低氧血症定义为血氧饱和度低于85%。3例患者在透析期间或透析后无低氧血症。5例患者在透析期间和透析后均出现低氧血症，2例患者仅在透析后阶段出现低氧血症。透析后阶段低氧血症发作的持续时间更长，程度更严重。我们得出结论，血液透析后阶段可发生明显的低氧血症。
