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血管生成因子作为肿瘤标志物。

Angiogenic factors as tumor markers.

作者信息

Nguyen M

机构信息

University of California, Los Angeles, USA.

出版信息

Invest New Drugs. 1997;15(1):29-37. doi: 10.1023/a:1005766511385.

DOI:10.1023/a:1005766511385
PMID:9195287
Abstract

The process of angiogenesis plays a critical role in tumor growth and metastasis. Recently, there has been much interest in the possible use of angiogenic growth factors as tumor markers. This paper will review the results thus far of attempts at measuring various angiogenic factors in bodily fluids. In the future, angiogenic factors will most likely be useful as a monitor of therapy and/or a predictor of outcome after cancer has been diagnosed.

摘要

血管生成过程在肿瘤生长和转移中起着关键作用。最近,人们对将血管生成生长因子用作肿瘤标志物的可能性产生了浓厚兴趣。本文将综述迄今为止在测量体液中各种血管生成因子方面的尝试结果。未来,血管生成因子很可能作为癌症诊断后治疗的监测指标和/或预后的预测指标发挥作用。

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Angiogenic factors as tumor markers.血管生成因子作为肿瘤标志物。
Invest New Drugs. 1997;15(1):29-37. doi: 10.1023/a:1005766511385.
2
Elevated levels of angiogenic cytokines in the plasma of cancer patients.
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Angiogenesis and angiogenic growth factors in Wilms tumor.肾母细胞瘤中的血管生成与血管生成生长因子
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Are basic fibroblast growth factor and vascular endothelial growth factor prognostic indicators in pediatric patients with malignant solid tumors?碱性成纤维细胞生长因子和血管内皮生长因子是小儿恶性实体瘤患者的预后指标吗?
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本文引用的文献

1
Diagnostic and prognostic role of basic fibroblast growth factor in Wilms' tumor patients.
Clin Cancer Res. 1995 Mar;1(3):327-31.
2
Elevated levels of the angiogenic peptide basic fibroblast growth factor in urine of bladder cancer patients.膀胱癌患者尿液中血管生成肽碱性成纤维细胞生长因子水平升高。
J Natl Cancer Inst. 1993 Feb 3;85(3):241-2. doi: 10.1093/jnci/85.3.241.
3
Serum and ascitic fluid levels of interleukin-1, interleukin-6, and tumor necrosis factor-alpha in patients with ovarian epithelial cancer.卵巢上皮癌患者血清及腹水中白细胞介素-1、白细胞介素-6和肿瘤坏死因子-α的水平
在MMTV-PyMT乳腺癌小鼠模型中使用(R)-[CPAQ]PET进行治疗反应评估。
EJNMMI Res. 2018 Apr 3;8(1):25. doi: 10.1186/s13550-018-0380-x.
4
Anti-tumor effects of ONC201 in combination with VEGF-inhibitors significantly impacts colorectal cancer growth and survival in vivo through complementary non-overlapping mechanisms.ONC201 联合 VEGF 抑制剂的抗肿瘤作用通过互补且非重叠的机制显著影响结直肠癌的体内生长和存活。
J Exp Clin Cancer Res. 2018 Jan 22;37(1):11. doi: 10.1186/s13046-018-0671-0.
5
Tumor-associated circulating microRNAs as biomarkers of cancer.肿瘤相关循环微小RNA作为癌症的生物标志物
Molecules. 2014 Feb 10;19(2):1912-38. doi: 10.3390/molecules19021912.
6
Platelet proteome and tumor dormancy: can platelets content serve as predictive biomarkers for exit of tumors from dormancy?血小板蛋白质组与肿瘤休眠:血小板内容物能否作为肿瘤休眠期退出的预测性生物标志物?
Cancers (Basel). 2010 May 11;2(2):842-58. doi: 10.3390/cancers2020842.
7
Analysis of EGF+61A>G polymorphism and EGF serum levels in Brazilian glioma patients treated with perillyl alcohol-based therapy.巴西胶质瘤患者接受普瑞巴林醇基治疗后,表皮生长因子+61A>G 多态性和表皮生长因子血清水平分析。
J Cancer Res Clin Oncol. 2012 Aug;138(8):1347-54. doi: 10.1007/s00432-012-1203-5. Epub 2012 Apr 6.
8
Isolation and proteomic analysis of platelets by SELDI-TOF MS.利用表面增强激光解吸电离飞行时间质谱法对血小板进行分离及蛋白质组分析。
Methods Mol Biol. 2012;818:153-70. doi: 10.1007/978-1-61779-418-6_12.
9
Tumor angiogenesis as a target for dietary cancer prevention.肿瘤血管生成作为饮食预防癌症的靶点。
J Oncol. 2012;2012:879623. doi: 10.1155/2012/879623. Epub 2011 Sep 29.
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Positron emission tomography imaging of cancer biology: current status and future prospects.正电子发射断层成像在癌症生物学中的应用:现状与展望。
Semin Oncol. 2011 Feb;38(1):70-86. doi: 10.1053/j.seminoncol.2010.11.005.
Cancer. 1993 Oct 15;72(8):2433-40. doi: 10.1002/1097-0142(19931015)72:8<2433::aid-cncr2820720822>3.0.co;2-l.
4
Urinary epidermal growth factor in patients with gliomas: significance of the factor as a glial tumor marker.
J Neurosurg. 1993 Sep;79(3):408-13. doi: 10.3171/jns.1993.79.3.0408.
5
Basic fibroblast growth factor secreted by an animal tumor is detectable in urine.
Cancer Res. 1993 Nov 1;53(21):5297-9.
6
Vascular endothelial growth factor/vascular permeability factor is detectable in the sera of tumor-bearing mice and cancer patients.
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7
Elevated basic fibroblast growth factor in the serum of patients with Duchenne muscular dystrophy.杜兴氏肌营养不良症患者血清中碱性成纤维细胞生长因子升高。
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Increased basic fibroblast growth factor in plasma from multiple endocrine neoplasia type 1: relation to pituitary tumor.
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Elevated serum levels of transforming growth factor-alpha in breast cancer patients.乳腺癌患者血清中转化生长因子-α水平升高。
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10
Serum levels of cytokines in patients with colorectal cancer: possible involvement of interleukin-6 and interleukin-8 in hematogenous metastasis.结直肠癌患者血清细胞因子水平:白细胞介素-6和白细胞介素-8可能参与血行转移。
J Gastroenterol. 1994 Aug;29(4):423-9. doi: 10.1007/BF02361238.