Gutberlet M, Venz S, Neuhaus R, Ehrenstein T, Lemke A J, Vogl T J, Hosten N, Neuhaus P, Felix R
Strahlenklinik und Poliklinik, Virchow-Klinikum, Medizinische Fakultät der Humboldt-Universität Berlin.
Rofo. 1997 May;166(5):411-6. doi: 10.1055/s-2007-1015450.
A prospective study was carried out to determine whether an improved assessment of the anatomy and flow velocity in the hepatic artery could be achieved by the administration of a capillary transversing contrast agent (Levovist) in patients after orthotopic liver transplantation.
In 21 (62%) of 34 patients after liver transplantation, only an insufficient visualisation of the hepatic artery was achieved. Therefore, a capillary transversing contrast agent was administered intravenously. Pre- and post-contrast peak velocity and Doppler frequency shift in the proper hepatic artery were measured and image quality of colour and spectral Doppler was assessed by a qualitative scale.
Image quality, with complete visualisation of hepatic artery in 79% (precontrast 38%) of all cases, was significantly improved (p < 0.01 (Wilcoxon test)) by the administration of a contrast agent.
Visualisation of the hepatic artery after orthotopic liver transplantation can be improved by the administration of Levovist. It allows a reliable measurement of peak velocity and Doppler frequency shift and helps to avoid further imaging.
进行一项前瞻性研究，以确定原位肝移植术后患者通过给予一种可穿越毛细血管的造影剂（Levovist）是否能够实现对肝动脉解剖结构和血流速度的更好评估。
34例肝移植术后患者中有21例（62%）肝动脉显影不佳。因此，经静脉给予一种可穿越毛细血管的造影剂。测量造影剂注射前后肝固有动脉的峰值速度和多普勒频移，并通过定性量表评估彩色和频谱多普勒的图像质量。
通过给予造影剂，图像质量显著改善（p < 0.01（Wilcoxon检验）），所有病例中有79%（造影前为38%）实现了肝动脉的完全显影。
给予Levovist可改善原位肝移植术后肝动脉的显影。它能够可靠地测量峰值速度和多普勒频移，并有助于避免进一步的成像检查。
