The Val985Met insulin-receptor variant in the Danish Caucasian population: lack of associations with non-insulin-dependent diabetes mellitus or insulin resistance.
作者信息
Hansen L, Hansen T, Clausen J O, Echwald S M, Urhammer S A, Rasmussen S K, Pedersen O
出版信息
Am J Hum Genet. 1997 Jun;60(6):1532-5. doi: 10.1086/515464.
Abstract
摘要
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本文引用的文献
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Insulin sensitivity index, acute insulin response, and glucose effectiveness in a population-based sample of 380 young healthy Caucasians. Analysis of the impact of gender, body fat, physical fitness, and life-style factors.380名年轻健康白种人群体样本中的胰岛素敏感性指数、急性胰岛素反应及葡萄糖效能。性别、体脂、体能及生活方式因素的影响分析。
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Enzyme immunoassay for intact human insulin in serum or plasma.血清或血浆中完整人胰岛素的酶免疫测定法。
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Methionine for valine substitution in exon 17 of the insulin receptor gene in a pedigree with familial NIDDM.
Diabetes. 1993 Mar;42(3):429-34. doi: 10.2337/diab.42.3.429.
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Insulin-mediated pseudoacromegaly: clinical and biochemical characterization of a syndrome of selective insulin resistance.胰岛素介导的假性肢端肥大症：一种选择性胰岛素抵抗综合征的临床和生化特征
J Clin Endocrinol Metab. 1993 Jun;76(6):1533-41. doi: 10.1210/jcem.76.6.8388881.
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Insulin resistance: interactions between obesity and a common variant of insulin receptor substrate-1.胰岛素抵抗：肥胖与胰岛素受体底物-1常见变异体之间的相互作用。
Lancet. 1995 Aug 12;346(8972):397-402. doi: 10.1016/s0140-6736(95)92779-4.
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A widespread amino acid polymorphism at codon 905 of the glycogen-associated regulatory subunit of protein phosphatase-1 is associated with insulin resistance and hypersecretion of insulin.蛋白磷酸酶-1糖原相关调节亚基第905位密码子处广泛存在的氨基酸多态性与胰岛素抵抗及胰岛素分泌过多有关。
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Detection of mutations in insulin-receptor gene in NIDDM patients by analysis of single-stranded conformation polymorphisms.通过单链构象多态性分析检测非胰岛素依赖型糖尿病患者胰岛素受体基因的突变。
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