Maclean H, Robinson L P, Wechsler A W, Goh A
Sydney Eye Hospital, Wooloomooloo, New South Wales.
Aust N Z J Ophthalmol. 1996 May;24(2):127-30. doi: 10.1111/j.1442-9071.1996.tb01566.x.
Corneal grafting is a standard treatment for visually disabling granular dystrophy. The visual results of this procedure are generally good, but can be marred by recurrences of granular deposits some years later. We report the results of phototherapeutic keratectomy (PTK) for recurrent granular dystrophy in three eyes from two patients and discuss the possibilities of treating de novo granular dystrophy with excimer laser.
The records of two patients (three eyes) treated with excimer PTK for recurrent granular deposits on the donor cornea were reviewed.
In all cases visual acuity was improved and repeat corneal grafting avoided. No significant complications occurred although one eye had further recurrence of granular deposits which was also successfully retreated with excimer PTK. Follow-up on these cases varies between five months and three years.
We believe that excimer PTK offers a simple, safe and repeatable way of restoring visual acuity to most cases of recurrent granular dystrophy. Visual recovery is fast and all the incumbent problems of repeat grafting are avoided.
角膜移植是治疗导致视力障碍的颗粒状角膜营养不良的标准方法。该手术的视觉效果通常良好，但几年后可能会因颗粒状沉积物复发而受到影响。我们报告了两名患者三只眼中复发性颗粒状角膜营养不良的光动力角膜切削术（PTK）的结果，并讨论了用准分子激光治疗原发性颗粒状角膜营养不良的可能性。
回顾了两名患者（三只眼）接受准分子PTK治疗供体角膜上复发性颗粒状沉积物的记录。
所有病例视力均有改善，避免了再次角膜移植。尽管有一只眼颗粒状沉积物再次复发，也成功地用准分子PTK再次治疗，但未发生明显并发症。这些病例的随访时间在5个月至3年之间。
我们认为准分子PTK为大多数复发性颗粒状角膜营养不良病例恢复视力提供了一种简单、安全且可重复的方法。视力恢复迅速，避免了再次移植的所有相关问题。
