Savaşan S, Tuzcu V, Warrier I, Karpawich P
Division of Hematology/Oncology, Children's Hospital of Michigan, Wayne State University School of Medicine, Detroit, USA.
J Pediatr Hematol Oncol. 1997 May-Jun;19(3):254-7. doi: 10.1097/00043426-199705000-00015.
Several side effects of intravenous immunoglobulin G (IVIG) therapy are known, but it has never been reported to be associated with cardiac rhythm abnormalities other than sinus tachycardia.
We describe the development of cardiac dysrhythmias during intravenous immunoglobulin G infusion in two children with thrombocytopenia. One of the patients had a history of supraventricular tachycardia, and the other had evidence suggestive of preexisting long QT syndrome.
Cardiac rhythm abnormalities may be exacerbated in individuals with preexisting cardiac problems by IVIG infusion, and such patients should be monitored closely during IVIG administration.
静脉注射免疫球蛋白G（IVIG）治疗的几种副作用是已知的，但从未有报道称其与除窦性心动过速以外的心律失常有关。
我们描述了两名血小板减少症患儿在静脉注射免疫球蛋白G期间发生心律失常的情况。其中一名患者有室上性心动过速病史，另一名患者有证据提示存在既往长QT综合征。
已有心脏问题的个体在静脉注射免疫球蛋白G时可能会使心律失常加重，此类患者在静脉注射免疫球蛋白G给药期间应密切监测。
