人恶性组织提取物中针对兔红细胞的凝集素。

Agglutinins to rabbit erythrocytes in extracts of human malignant tissues.

作者信息

Wesenberg F, Tönder O

出版信息

Acta Pathol Microbiol Scand C. 1977 Oct;85(5):389-94. doi: 10.1111/j.1699-0463.1977.tb03658.x.

DOI:10.1111/j.1699-0463.1977.tb03658.x

PMID:920190

Abstract

Agglutinins to rabbit erythrocytes in extracts from human malignant tissues were identified as the naturally occurring IgG antibodies in human serum to rabbit erythrocytes. This was revealed by agglutination, absorption, antiglobulin and inhibition tests, immunization of rabbits and immunochemical analyses. The agglutinins can therefore be used as convenient markers for both extracellular immunoglobulin and unspecifically bound immunoglobulin in tumour tissues. Apparently the extracts also contained small amounts of IgA antibodies to rabbit erythrocytes.

摘要

在人恶性组织提取物中，针对兔红细胞的凝集素被鉴定为人血清中天然存在的针对兔红细胞的IgG抗体。这通过凝集试验、吸收试验、抗球蛋白试验、抑制试验、兔免疫和免疫化学分析得以揭示。因此，这些凝集素可用作肿瘤组织中细胞外免疫球蛋白和非特异性结合免疫球蛋白的便捷标记物。显然，提取物中还含有少量针对兔红细胞的IgA抗体。