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非体外循环下再次冠状动脉搭桥术

Reoperative coronary artery bypass without cardiopulmonary bypass.

作者信息

Mohr R, Moshkovitz Y, Gurevitch J, Benetti F J

机构信息

Department of Cardiac Surgery, The Chaim Sheba Medical Center, Tel Hashomer, Israel.

出版信息

Ann Thorac Surg. 1997 Jun;63(6 Suppl):S40-3. doi: 10.1016/s0003-4975(97)00429-3.

Abstract

BACKGROUND

Conventional reoperative coronary artery bypass grafting using cardiopulmonary bypass carries relatively high mortality and morbidity.

METHODS

Seventy-seven patients underwent coronary artery bypass grafting without cardiopulmonary bypass in two centers between 1988 and 1994. Mean age was 65 +/- 8 years (mean +/- SD). Twenty-three (30%) were operated on urgently and 7 (9%) emergently. Nine (12%) were referred for operation up to 2 weeks after acute myocardial infarction. Fifteen patients (19%) had an ejection fraction less than or equal to 0.35. The mean number of grafts per patient was 1.7 (range, 1 to 3), and the internal mammary artery was used in 66 patients (86%). Only 18 patients (23%) received at least one graft to the circumflex artery. Hospital stay was 7.4 +/- 6.5 days.

RESULTS

Early events included operative death in 4 patients (5.2%), nonfatal myocardial infarction in 3 (3.9%), sternal infection in 2 (2.6%), and stroke in 0 (0%). Follow-up (30 +/- 15 months) showed 11 deaths (5 cardiac, 6 noncardiac), 2 (2.8%) nonfatal myocardial infarctions, and return of angina in 9 patients (12.8%). One- and 4-year actuarial survival rates were 90% and 69%, respectively.

CONCLUSIONS

Reoperative coronary artery bypass grafting without cardiopulmonary bypass has acceptable early and midterm outcome, and should be considered a viable alternative for properly selected patients.

摘要

背景

采用体外循环进行的传统再次冠状动脉旁路移植术具有相对较高的死亡率和发病率。

方法

1988年至1994年间,77例患者在两个中心接受了非体外循环冠状动脉旁路移植术。平均年龄为65±8岁(均值±标准差)。23例(30%)为急诊手术,7例(9%)为紧急手术。9例(12%)在急性心肌梗死后2周内被转诊接受手术。15例患者(19%)的射血分数小于或等于0.35。每位患者平均移植血管数为1.7条(范围为1至3条),66例患者(86%)使用了乳内动脉。仅18例患者(23%)接受了至少一条至回旋支动脉的移植血管。住院时间为7.4±6.5天。

结果

早期事件包括4例患者(5.2%)手术死亡,3例(3.9%)非致命性心肌梗死,2例(2.6%)胸骨感染,0例(0%)中风。随访(30±15个月)显示11例死亡(5例心脏相关,6例非心脏相关),2例(2.8%)非致命性心肌梗死,9例患者(12.8%)心绞痛复发。1年和4年的精算生存率分别为90%和69%。

结论

非体外循环再次冠状动脉旁路移植术具有可接受的早期和中期结果,对于适当选择的患者应被视为一种可行的替代方案。

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