Moshkovitz Y, Sternik L, Paz Y, Gurevitch J, Feinberg M S, Smolinsky A K, Mohr R
Department of Cardiac Surgery and The Heart Institute, The Chaim Sheba Medical Center, Tel Hashomer, Israel.
Ann Thorac Surg. 1997 Jun;63(6 Suppl):S44-7. doi: 10.1016/s0003-4975(97)00432-3.
Conventional coronary artery bypass grafting using cardiopulmonary bypass carries relatively high mortality and morbidity for patients with left ventricular dysfunction.
Seventy-five patients with ejection fraction less than or equal to 0.35 underwent primary coronary artery bypass grafting without cardiopulmonary bypass between December 1991 and December 1994. Thirty-two patients (43%) had congestive heart failure, 11 (15%) were referred for operation within the first 24 hours of evolving myocardial infarction, and 21 (28%) up to 1 week after acute myocardial infarction. Eighteen patients (24%), 6 of whom were in cardiogenic shock, underwent emergency operations.
Mean number of grafts/patient was 1.9 (range, 1 to 4), and internal mammary artery was used in 66 patients (85%). Only 17 patients (23%) received a graft to a circumflex marginal artery. Two patients (2.7%) died perioperatively, and 1 (1.3%) sustained stroke. At mean follow-up of 28 months, 13 patients had died, and angina had returned in 7 (10.5%). One- and four-year actuarial survival was 96% and 73%, respectively.
Coronary artery bypass grafting without cardiopulmonary bypass is a viable alternative to conventional coronary artery bypass grafting particularly for patients with extreme left ventricular dysfunction or those with coexisting risk factors, such as acute myocardial infarction and cardiogenic shock.
对于左心室功能不全的患者,使用体外循环进行传统冠状动脉旁路移植术的死亡率和发病率相对较高。
1991年12月至1994年12月期间,75例射血分数小于或等于0.35的患者接受了非体外循环下的初次冠状动脉旁路移植术。32例患者(43%)患有充血性心力衰竭,11例(15%)在急性心肌梗死发病的最初24小时内被转诊进行手术,21例(28%)在急性心肌梗死后1周内进行手术。18例患者(24%)接受了急诊手术,其中6例处于心源性休克状态。
每位患者平均移植血管数为1.9(范围为1至4),66例患者(85%)使用了乳内动脉。仅17例患者(23%)接受了旋支边缘动脉的血管移植。2例患者(2.7%)围手术期死亡,1例(1.3%)发生中风。平均随访28个月时,13例患者死亡,7例(10.5%)心绞痛复发。1年和4年的精算生存率分别为96%和73%。
非体外循环冠状动脉旁路移植术是传统冠状动脉旁路移植术的一种可行替代方法,尤其适用于左心室功能极差或存在急性心肌梗死和心源性休克等并存危险因素的患者。