Mendoza H, Acha V, Vives R, Sánchez J, Berasategui J I, Acero S
Servicio de Medicina Interna, Hospital Virgen del Camino, Pamplona.
An Med Interna. 1997 May;14(5):244-6.
The acute febrile neutrophilic dermatosis or Sweet syndrome, initially described in 1964 by Robert Sweet (1). It is characterized fever, neutrophilic leucocytosis, abrupt appearance of erythematous, painful, cutaneous plaquets and dense dermal infiltrate consisting of mature neutrophils without vasculitis sings. Malignancy has been described in the 10-15% of the reported cases. We report our series of 6 patients diagnosticated of this illness in our department. One of this patients has Sweet syndrome associated with a malignancy disorder. All of them had diagnostic criteria of the described disease and had good response to corticotherapy. We also report a bibliographic review of this infrequent syndrome.
急性发热性嗜中性皮病即斯威特综合征,于1964年由罗伯特·斯威特首次描述(1)。其特征为发热、嗜中性白细胞增多、突然出现的红斑性、疼痛性皮肤斑块以及由成熟嗜中性粒细胞组成的密集真皮浸润,无血管炎体征。在已报道的病例中,10% - 15% 的患者伴有恶性肿瘤。我们报告了在我们科室诊断的6例该疾病患者系列。其中1例患者的斯威特综合征与恶性肿瘤性疾病相关。所有患者均符合所描述疾病的诊断标准,且对皮质激素治疗反应良好。我们还报告了对这种罕见综合征的文献综述。