Detterbeck F C
Division of Cardiothoracic Surgery, University of North Carolina School of Medicine, Chapel Hill, USA.
Ann Thorac Surg. 1997 Jun;63(6):1810-8. doi: 10.1016/s0003-4975(97)00360-3.
Primary carcinomas arising in the apex of the lung (Pancoast tumors) have attracted attention because of the characteristic syndrome that is produced by local extension into the chest wall and the brachial plexus. This article reviews the history of the treatment of this disease, the natural history of untreated patients, and the diagnosis of Pancoast tumors. The published data on results, prognostic factors, and technical aspects of treatment with combined irradiation and operation are examined, as well as those pertaining to treatment with irradiation alone.
起源于肺尖的原发性癌(潘科斯特瘤)因其局部蔓延至胸壁和臂丛神经所产生的特征性综合征而受到关注。本文回顾了该疾病的治疗史、未经治疗患者的自然病程以及潘科斯特瘤的诊断。同时研究了关于联合放疗与手术治疗的结果、预后因素及技术方面的已发表数据,以及单纯放疗治疗的相关数据。