Zhang D, Chen Y, Tu C
Department of Respiratory Medicine, Zhongshan Hospital, Shanghai Medical University.
Zhonghua Zhong Liu Za Zhi. 1996 Mar;18(2):123-6.
To assess the value of thoracoscopy in malignant pleural effusions, the procedure and results of thoracoscopy by using a fiberoptic bronchoscope and a rigid cold-light thoracoscope in 130 cases with malignant pleural effusion are reported. The overall diagnostic rate was 91.5% (119/130). The malignant pleural mesothelioma in 24 cases and metastatic cancers in 95 cases were histopathologically confirmed. Talcum powder, tetracycline and Corynebacterium parvum were separately sprayed through thoracoscope into pleural cavity in 69, 10 and 10 patients, and the success rates of complete and lasting pleurodesis were 87.0%, 5/10 and 8/10 respectively. Postoperative complications included transient fever and chest pain, local subcutaneous emphysema in 6 cases and tumor seeding at thoracoscopy site in 4 cases. It is concluded that thoracoscopy is simple, safe, reliable and of high practical value in the diagnosis of malignant pleural effusions and in assessment before exploratory thoracotomy, and that transendoscopical administration of drugs for pleurodesis is a very effective method for controlling malignant pleural effusions. The efficacy of the talc poudrage is better than tetracycline and Corynebacterium parvum.
为评估胸腔镜检查在恶性胸腔积液中的价值,本文报告了应用纤维支气管镜和硬式冷光胸腔镜对130例恶性胸腔积液患者进行胸腔镜检查的操作过程及结果。总体诊断率为91.5%(119/130)。经组织病理学确诊24例为恶性胸膜间皮瘤,95例为转移性癌。分别对69例、10例和10例患者经胸腔镜向胸腔内喷洒滑石粉、四环素和短小棒状杆菌,完全性和持久性胸膜固定术的成功率分别为87.0%、5/10和8/10。术后并发症包括短暂发热、胸痛,6例出现局部皮下气肿,4例在胸腔镜检查部位出现肿瘤种植。结论:胸腔镜检查在恶性胸腔积液的诊断及开胸探查术前评估中操作简便、安全可靠、实用价值高,经内镜给药进行胸膜固定术是控制恶性胸腔积液的一种非常有效的方法。滑石粉喷洒的疗效优于四环素和短小棒状杆菌。