Plotnikov M B, Smol'iakova V I, Chernysheva G A
Eksp Klin Farmakol. 1997 Mar-Apr;60(2):72-4.
Experiments were conducted on Wistar rats to study the effect of intravenous infusion of polyosm (solution of polyethyleneoxide 400) on the parameters of brain tissue edema-swelling (according to impedancemetry findings) and the local cerebral blood flow on a model of acute hypertensive encephalopathy. Under such conditions the drug hastened involution of edema-swelling of the brain tissue and prevented a decrease in cerebral blood flow.
