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不同强度致癌暴露下人类癌症的年龄分布。

The age distribution of human cancer for carcinogenic exposures of varying intensity.

作者信息

Whittemore A S

出版信息

Am J Epidemiol. 1977 Nov;106(5):418-32. doi: 10.1093/oxfordjournals.aje.a112484.

DOI:10.1093/oxfordjournals.aje.a112484
PMID:920729
Abstract

The time and age dependence of cancer incidence rates resulting from various type of carcinogenic exposure are calculated and compared with observed cancer incidence rates. Implications for the detection of increased cancer incidence are discussed. The calculations assume that exposure affects one of several changes necessary for malignant cell transformation.

摘要

计算了由各种致癌暴露类型导致的癌症发病率的时间和年龄依赖性，并与观察到的癌症发病率进行了比较。讨论了对检测癌症发病率增加的影响。计算假设暴露会影响恶性细胞转化所需的几种变化之一。

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