Babcook C J, Drake C M, Goldstein R B
Department of Diagnostic Radiology, University of California, Davis Medical Center, Sacramento 95817, USA.
AJR Am J Roentgenol. 1997 Jul;169(1):207-10. doi: 10.2214/ajr.169.1.9207526.
Our objective was to determine whether the level of the spinal defect influences ventricular size in fetuses with myelomeningoceles.
Sonograms of 51 fetuses with open spina bifida were reviewed to determine the gestational age, ventricular atrial diameter, severity of posterior fossa deformity, and the level of the spinal defect. Four categories for spinal defect level were used: sacral, low lumbar, high lumbar, and thoracic. Regression models for ventricular atrial diameter were fit, adjusting for gestational age, posterior fossa deformity, and spinal defect level. A Fisher's exact test was used to investigate a relationship between the level of the spinal defect and the severity of the posterior fossa deformity.
Spinal defect level was distributed among the four categories as follows: sacral (n = 7), low lumbar (n = 30), high lumbar (n = 10), and thoracic (n = 4). The level of the spinal defect did not significantly affect ventricular size (p > .1), and the level of the spinal defect did not show any relationship to the severity of the posterior fossa deformity (p > .8).
The level of the spinal defect does not independently affect the degree of ventriculomegaly or severity of the posterior fossa deformity in fetuses with myelomeningoceles.
我们的目的是确定脊柱缺损的水平是否会影响脊髓脊膜膨出胎儿的脑室大小。
回顾了51例开放性脊柱裂胎儿的超声检查结果，以确定胎龄、心室心房直径、后颅窝畸形的严重程度以及脊柱缺损的水平。脊柱缺损水平分为四类：骶骨、低位腰椎、高位腰椎和胸椎。建立心室心房直径的回归模型，对胎龄、后颅窝畸形和脊柱缺损水平进行校正。采用Fisher精确检验研究脊柱缺损水平与后颅窝畸形严重程度之间的关系。
脊柱缺损水平在四类中的分布如下：骶骨（n = 7）、低位腰椎（n = 30）、高位腰椎（n = 10）和胸椎（n = 4）。脊柱缺损水平对心室大小无显著影响（p > .1），且脊柱缺损水平与后颅窝畸形严重程度无任何关系（p > .8）。
脊柱缺损水平不会独立影响脊髓脊膜膨出胎儿的脑室扩大程度或后颅窝畸形的严重程度。
