He S T, He F Z, Wu C R
Hunan Academy of Traditional Chinese Medicine, Changsha.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 1996 Mar;16(3):132-5.
Sixty cases of rotaviral enteritis treated with Qiwei Baizhu Powder (QWBZP) revealed a better efficacy than that treated with Oral Rehydration solution (ORS, chi 2 = 6.07, P < 0.05). The content of Na+ and glucose as well as number of patients with positive human rotavirus (HRV) antigen in faeces in QWBZP group were less than that in ORS group (chi 2 = 18.09, P < 0.05). In experimental study, QWBZP was found to be effective in treating HRV enteritis of newborn NIH mice in vivo, as compared with the control groups, the mortality of mice was decreased by 73.3%, the content of Na+ and glucose as well as number of mice with positive HRV antigen in faeces was markedly reduced, the pathological changes of intestine such as the damage of small intestinal mucosa and the exfoliation of intestinal villi were also obviously alleviated.
用七味白术散(QWBZP)治疗60例轮状病毒性肠炎,疗效优于口服补液盐(ORS,χ² = 6.07,P < 0.05)。七味白术散组粪便中Na⁺和葡萄糖含量以及人轮状病毒(HRV)抗原阳性患者数量均少于口服补液盐组(χ² = 18.09,P < 0.05)。实验研究发现,七味白术散对新生NIH小鼠体内HRV肠炎有治疗作用,与对照组相比,小鼠死亡率降低73.3%,粪便中Na⁺和葡萄糖含量以及HRV抗原阳性小鼠数量明显减少,小肠黏膜损伤、肠绒毛脱落等肠道病理变化也明显减轻。