Morsink P L, Verkerke G J, Grootenboer H J, Mihaylov D, Rakhorst G
Faculty of Mechanical Engineering, Department of Biomechanics, University of Twente, The Netherlands.
Int J Artif Organs. 1997 May;20(5):277-84.
Mechanical heart assistance, performed by the PUlsatile CAtheter (PUCA) pump, chronologically takes place by sucking blood from the left ventricle and ejecting it into the ascending aorta. Within the pump activity the problem of hemolysis and clotting is encountered. In this study the influence of valve geometry on blood cell damage and stagnant zones has been investigated. A variable valve length coupled to a catheter ejection gap and a variable valve angle have been studied. In case of the studied valve, optimal parameter values have been determined. Compared to small catheter ejection gaps with a corresponding valve length, blood damage is found to be less for large ejection gaps with corresponding valve dimensions. In systole a valve positioned in a 0 degree angle proves to be best, whereas in diastole a +20 degree angle is preferable. Because the system is operating in both systole and diastole, a 0 degree angle valve is applied.
由脉动导管（PUCA）泵实施的机械心脏辅助按时间顺序进行，即从左心室抽吸血液并将其喷射到升主动脉中。在泵的运行过程中会遇到溶血和凝血问题。在本研究中，研究了瓣膜几何形状对血细胞损伤和停滞区域的影响。研究了与导管喷射间隙相关的可变瓣膜长度和可变瓣膜角度。对于所研究的瓣膜，已确定了最佳参数值。与具有相应瓣膜长度的小导管喷射间隙相比，发现具有相应瓣膜尺寸的大喷射间隙对血液的损伤较小。在收缩期，0度角的瓣膜被证明是最佳的，而在舒张期，+20度角更可取。由于该系统在收缩期和舒张期都运行，因此应用了0度角的瓣膜。
