对一名马拉硫磷中毒患者使用依酚氯铵进行神经肌肉逆转的评估。

An evaluation of neuromuscular reversal with edrophonium in a patient with malathion intoxication.

作者信息

Matsukawa S, Hashimoto Y, Kato M, Hoshi K, Satoh D, Horinouchi T, Satoh S, Saishu T

机构信息

Division of Intensive Care Medicine, Tohoku University Hospital, Sendai, Japan.

出版信息

Tohoku J Exp Med. 1997 Apr;181(4):467-9. doi: 10.1620/tjem.181.467.

DOI:10.1620/tjem.181.467

PMID:9210253

Abstract

We evaluated the neuromuscular reversal with edrophonium using peripheral nerve stimulator and recorder in a patient with malathion intoxication. Edrophonium 10 mg i.v. caused an increase in single twitch tension by 76% of the control during the recovery phase from an acute cholinergic crisis 16 days after ingestion of malathion solution. The present study indicated that edrophonium test seems to be a reliable monitoring in evaluating neuromuscular reversal in the patient with acute malathion insecticide poisoning.

摘要

我们使用外周神经刺激器和记录仪，对一名马拉硫磷中毒患者使用依酚氯铵进行神经肌肉逆转评估。静脉注射10毫克依酚氯铵后，在摄入马拉硫磷溶液16天后的急性胆碱能危象恢复期，单收缩张力比对照增加了76%。本研究表明，依酚氯铵试验似乎是评估急性马拉硫磷杀虫剂中毒患者神经肌肉逆转的可靠监测方法。