• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Salt-independent adsorption of human serum proteins on cyanocarbon gels.

作者信息

Berna P P, Porath J

机构信息

Biochemical Separation Centre, Uppsala University, Sweden.

出版信息

J Chromatogr B Biomed Sci Appl. 1997 Jun 6;693(2):277-85. doi: 10.1016/s0378-4347(97)00030-3.

DOI:10.1016/s0378-4347(97)00030-3
PMID:9210430
Abstract

Electron donor acceptor gels based on cyanocarbons have been tested for human serum protein adsorption in the absence of salt-promotion by water-structuring salt. This phenomenon was compared with a normal adsorption process in the presence of salt. The tricyanoaminopropene-divinyl sulfone-agarose displayed unusual protein adsorption properties as binding could occur both independently or dependently of the salt-promotion. The absence of hydrophobic or ionic character of the salt-independent interaction suggests an electron donor acceptor adsorption mechanism which is shown, for the first time, to occur independently of salt-promotion in aqueous solution. Study of the protein adsorption specificity showed similar protein selectivity for the fractions adsorbed in both conditions.

摘要

相似文献

1
Salt-independent adsorption of human serum proteins on cyanocarbon gels.
J Chromatogr B Biomed Sci Appl. 1997 Jun 6;693(2):277-85. doi: 10.1016/s0378-4347(97)00030-3.
2
Comparison of the protein adsorption selectivity of salt-promoted agarose-based adsorbents. Hydrophobic, thiophilic and electron donor-acceptor adsorbents.
J Chromatogr A. 1998 Mar 27;800(2):151-9. doi: 10.1016/s0021-9673(97)01130-8.
3
Cyanocarbons as ligands for electron donor acceptor chromatography of human serum proteins.
J Chromatogr A. 1996 Nov 8;753(1):57-62. doi: 10.1016/s0021-9673(96)00515-8.
4
Salt-promoted adsorption of proteins onto amphiphilic agarose-based adsorbents. II. Effects of salt and salt concentration.
J Chromatogr A. 1998 Apr 17;803(1-2):83-93. doi: 10.1016/s0021-9673(97)01088-1.
5
Covalent chromatography and salt-promoted thiophilic adsorption.
Anal Biochem. 1989 Feb 1;176(2):330-7. doi: 10.1016/0003-2697(89)90318-7.
6
Polyol-promoted adsorption of serum proteins to amphiphilic agarose-based adsorbents.
J Chromatogr A. 1997 Mar 14;764(2):193-200. doi: 10.1016/s0021-9673(96)00933-8.
7
Salt-independent binding of antibodies from human serum to thiophilic heterocyclic ligands.
J Chromatogr B Biomed Sci Appl. 1998 May 29;709(2):189-96. doi: 10.1016/s0378-4347(98)00109-1.
8
Behaviour of human immunoglobulin G subclasses on thiophilic gels: comparison with hydrophobic interaction chromatography.人免疫球蛋白G亚类在嗜硫凝胶上的行为：与疏水相互作用色谱法的比较
J Chromatogr. 1993 Jul 2;616(2):197-204. doi: 10.1016/0378-4347(93)80386-i.
9
Thiophilic adsorption: a comparison of model protein behavior.
Biochemistry. 1987 Nov 3;26(22):7199-204. doi: 10.1021/bi00396a049.
10
Cosolvent-induced adsorption and desorption of serum proteins on an amphiphilic mercaptomethylene pyridine-derivatized agarose gel.助溶剂诱导血清蛋白在两亲性巯基亚甲基吡啶衍生化琼脂糖凝胶上的吸附和解吸
Arch Biochem Biophys. 1996 Jun 1;330(1):188-92. doi: 10.1006/abbi.1996.0241.