Oscarsson S, Kårsnäs P
Department of Chemical Engineering, Mälardalen University, Eskilstuna, Sweden.
J Chromatogr A. 1998 Apr 17;803(1-2):83-93. doi: 10.1016/s0021-9673(97)01088-1.
The effects of different types of salts and salt concentrations on the selectivity in the adsorption of serum proteins have been compared for the amphiphilic agarose-based adsorbents Phenyl-Sepharose, Octyl-Sepharose, butyl-agarose and mercaptopyridine-derivatized agarose. By use of multivariate analysis, the complex interrelationships for the different combined effects were evaluated. From these analyses conclusions about similarities and/or dissimilarities in the mechanisms involved in adsorption of proteins on respective adsorbent were made.
